Peripartum Management of Neonatal Pierre Robin Sequence

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Louis F Insalaco1, Andrew R Scott2

  • 1Department of Otolaryngology-Head and Neck Surgery, Boston Medical Center, 830 Harrison Avenue, First Floor, Boston, MA 02118, USA.

Clinics in Perinatology
|November 7, 2018
PubMed

Insights

Pierre Robin sequence (PRS) is a congenital condition affecting airway and feeding. This article reviews the background, diagnosis, and management trends for PRS.

Area of Science:

  • Medical Genetics
  • Pediatric Congenital Disorders
  • Craniofacial Abnormalities

Background:

  • Pierre Robin sequence (PRS) is a congenital condition defined by micrognathia, glossoptosis, and cleft palate.
  • These anomalies significantly impact infant airway patency and feeding capabilities.
  • The severity and presentation of PRS can vary widely among affected individuals.

Purpose of the Study:

  • To elucidate the fundamental nature and background of Pierre Robin sequence.
  • To provide a comprehensive overview of historical and contemporary approaches to PRS diagnosis.
  • To examine evolving trends in the management strategies for PRS.

Main Methods:

  • Literature review of existing studies on Pierre Robin sequence.
  • Analysis of diagnostic criteria and advancements over time.
  • Synthesis of current and historical management practices.

Main Results:

  • Detailed description of the etiological factors and developmental origins of PRS.
  • Identification of key diagnostic markers and evolving imaging techniques.
  • Compilation of diverse management options, from conservative to surgical interventions.

Conclusions:

  • Understanding the background of PRS is crucial for effective clinical management.
  • Diagnostic and management strategies for PRS have evolved significantly.
  • A multidisciplinary approach is essential for optimizing outcomes in patients with PRS.

Keywords:
Cleft palateGlossoptosisMicrognathiaPierre Robin sequence

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