Auditory disorders and future therapies with delivery systems
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Updated: Feb 3, 2026

Optogenetic Stimulation of the Auditory Nerve
Published on: October 8, 2014
Jung-Hwan Lee1,2,3, Min Young Lee4,5, Yohan Lim1
1Institute of Tissue Regeneration Engineering (ITREN), Dankook University, Cheonan, Republic of Korea.
Abstract:
Auditory function takes a major part in human life. While sensorineural hearing loss is related with many factors including genetic disorders, age and noise, the clear causes are not well understood. Even more, the currently available treatments with drugs cause side effects, which thus are considered suboptimal. Here, we communicate the delivery systems with biomaterials that can be possible therapeutic options to restore hearing and vestibular functions. We introduce briefly the various pathological factors related with hearing loss and the limitation of current therapies, detail the recent studies on delivery systems including nanoparticles and hydrogels and discuss future clinical availability.
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