Related Experiment Video

Updated: Feb 3, 2026

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients
05:48

The Adventures of Fundi Intervention Based on the Cognitive and Emotional Processing in Attention Deficit Hyperactive Disorder Patients

Published on: June 12, 2020

6.5K

The Prevalence and Effect of Comorbid Cystic Fibrosis and Attention Deficit Hyperactivity Disorders on

Nicole Spitzer1, Timothy B Legare2, Priyanshi Patel3

  • 1Ophthalmology, University of Central Florida College of Medicine, Orlando, USA.

Cureus
|November 7, 2018
PubMed

Insights

Pediatric cystic fibrosis (CF) patients with attention-deficit/hyperactivity disorder (ADHD) showed improved lung function (FEV1%pred) compared to those without ADHD. Further research is needed to understand ADHD

Area of Science:

  • Pediatric Pulmonology
  • Neurodevelopmental Disorders
  • Chronic Disease Management

Background:

  • Attention-deficit/hyperactivity disorder (ADHD) prevalence in pediatric cystic fibrosis (CF) patients mirrors the general population.
  • The impact of ADHD on CF treatment adherence and patient outcomes remains under-explored.

Purpose of the Study:

  • To investigate the association between comorbid ADHD and clinical outcomes in pediatric CF patients.
  • To compare pulmonary function, BMI, and hospitalization rates between CF patients with and without ADHD.

Main Methods:

  • Retrospective review of two matched cohorts: pediatric patients with CF/ADHD and CF-only.
  • Analysis included forced expiratory volume in one-second percent predicted (FEV1%pred), BMI percentile, and hospitalizations.
  • Age and sex matching was performed based on the most recent pulmonary office visit.

Main Results:

  • A total of 46 pediatric CF patients with ADHD were analyzed against a matched CF-only cohort.
  • No significant differences were found in total hospital admissions or BMI percentiles between groups.
  • A statistically significant improvement in FEV1%pred was observed in the CF/ADHD cohort (84%) compared to the CF-only cohort (74%).

Conclusions:

  • Comorbid ADHD in pediatric CF patients is associated with significantly better lung function (FEV1%pred).
  • While not statistically significant, hospitalization rates and BMI did not differ between groups.
  • Further research is warranted to elucidate the mechanisms and implications of ADHD on CF outcomes.
Abstract

Keywords:
adhdadherenceattention deficit hyperactivity disordercystic fibrosistreatment compliance

More Related Videos

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis07:56

Rectal Organoid Morphology Analysis ROMA: A Diagnostic Assay in Cystic Fibrosis

Published on: June 10, 2022

3.3K
Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD10:02

Event Related Potentials ERPs and other EEG Based Methods for Extracting Biomarkers of Brain Dysfunction: Examples from Pediatric Attention Deficit/Hyperactivity Disorder ADHD

Published on: March 12, 2020

16.8K

Related Concept Videos

Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....
986
Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
874
Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
541
Hospitals-II00:59

Hospitals-II

Hospitals provide inpatient and outpatient services. Inpatient services provide care to patients that stay in the hospital for an extended period, ranging from days to months. Examples of inpatient services include intensive care units, hospital wards, or surgeries. Outpatient services provide care to patients who come to a hospital for a diagnostic or treatment but do not stay overnight —for example, diagnostic tests, surgical procedures, or health education.
Nurses that work in...
1.2K
Hospitals-I01:28

Hospitals-I

Hospitals offer medical and surgical care to the sick and injured, along with accommodation while they recover. At the same time, they also provide outpatient, emergency, psychiatric, and rehabilitation services to meet various community needs. In addition to providing medical care, hospitals also act as hubs for medical research and training. Hospitals use clinical procedures and evidence-based practice standards to deliver patient care. To deliver safe and efficient care, a nurse must stay up...
1.6K
Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.9K