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Published on: January 29, 2018
Fatal intussusception in infancy: forensic implications
Milenko Bogdanović1, Miloš Blagojević2, Jelena Kuzmanović3
1Institute of Forensic Medicine "Milovan Milovanović", University of Belgrade - School of Medicine, 31a Deligradska str., Belgrade, 11000, Serbia. milenkobogdanovic88@live.com.
Insights
Intussusception, a common cause of infant intestinal obstruction, can be fatal. This case highlights rapid deterioration and death from intestinal necrosis and shock, emphasizing the need for prompt diagnosis in infants.
Area of Science:
- Pediatrics
- Gastroenterology
- Pathology
Background:
- Intussusception is a leading cause of intestinal obstruction in infants and young children.
- Fatalities, though rare, are linked to complications like peritonitis, sepsis, shock, or fluid imbalance.
Observation:
- An eight-month-old infant presented with vomiting and fever, initially managed as an outpatient.
- The infant's condition rapidly worsened over 9-10 hours, leading to hyperpyrexia and stupor.
- The infant died 15 hours after symptom onset, prior to reaching definitive care.
Findings:
- Autopsy revealed an 8 cm ileocecal intussusception.
- No evidence of peritonitis was found.
- Intestinal necrosis and shock secondary to obstruction were identified as the cause of death.
Implications:
- This case underscores the potential for rapid, fatal progression of intussusception in infants.
- Highlights the critical importance of timely diagnosis and intervention for pediatric intestinal obstruction.
- Emphasizes that even without typical acute abdomen signs, severe outcomes are possible.
Abstract:
Intussusception is one of the most common causes of intestinal obstructions in younger children, especially infants. Though rare, fatalities due to intussusception are known to be caused by intestinal obstruction associated with peritonitis, generalized sepsis and shock from intestinal infarction due to disruption in blood supply or electrolyte and fluid imbalance. An eight-month-old female infant, who initially presented with a single episode of vomiting and fever (37.8 °C), was examined as an outpatient at the department of pediatrics of a general hospital. Clinical examination revealed no characteristic features of acute abdomen, so the child was sent home. Nine to ten hours later her condition deteriorated: she became hyperpyretic and stuporous. On her way to the University Children's Hospital, the infant died; the death was confirmed upon admission, i.e. some 15 h after the onset of symptoms. The autopsy revealed an 8 cm long intussusception of the distal part of the ileum to the cecum. There was no gross or microscopic evidence of peritonitis at autopsy. The shock caused by intestinal obstruction with consequent intestinal necrosis was considered to be the cause of death.
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