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Ultrasonic-assisted synthesis and DNA interaction studies of two new Ru complexes; RuO2 nanoparticles preparation
Jun-Jie Xue1, Fahime Bigdeli2, Jian-Ping Liu1
1College of Chemistry & Materials Engineering, Wenzhou University, Wenzhou 325035, PR China.
Aim:
To study of the interactions of two new ruthenium(II) complexes (C1 and C2) with calf thymus (CT)-DNA; production of RuO2 nanoparticles using the complexes precursor.
Materials & Methods:
Complex C1 was characterized by x-ray crystallography. The binding of the complexes with (CT)-DNA was studied using techniques that include electronic absorption spectra, fluorescence and redox behavior. The preparation of RuO2 nanoparticles was carried out by thermal decomposition.
Results:
The interaction mode of DNA with complexes is the type of electrostatic. It was revealed that sonication of the samples, before thermal decomposition, has been affected the morphologies and sizes of the resulting nanoparticles.
Conclusion:
The complexes are capable of interaction with DNA molecules and they have a good potential to prepare nanostructures.
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