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Phytochemicals in Anticancer Drug Development
Rohit Dutt1, Vandana Garg2, Naveen Khatri3
1Department of Pharmacy, G.D. Goenka University, Gurgaon-122103, India.
Anti-Cancer Agents in Medicinal Chemistry
|November 7, 2018
Summary
Phytochemicals offer safer alternatives to conventional cancer therapies, with various plant compounds showing potent anticancer activity. Further exploration of these natural agents could lead to new cancer treatments with fewer side effects.
Area of Science:
- Phytochemistry
- Oncology
- Pharmacology
Background:
- Cancer remains a leading global cause of mortality despite advances in conventional treatments.
- Phytochemicals are increasingly recognized as effective and safer therapeutic agents for various diseases.
- Plant-derived compounds offer potential advantages over synthetic drugs in cancer therapy.
Purpose of the Study:
- To review the current status and potential of phytochemicals in cancer therapy.
- To highlight phytochemicals as a source of safer anticancer agents.
- To discuss the role of plant-derived compounds in overcoming limitations of current chemotherapy.
Main Methods:
- Categorization of phytochemicals based on their constituent groups (alkaloids, polyphenols, saponins, tannins, terpenoids).
- Review of existing literature on the anticancer activities of various phytochemicals.
- Analysis of the potential of plant-derived compounds in cancer treatment.
Main Results:
- Phytochemicals exhibit diverse anticancer activities.
- Plant-derived compounds can be used alone or in combination with conventional therapies.
- The exploration of the plant kingdom can accelerate the development of novel anticancer agents.
Conclusions:
- Phytochemicals present a promising avenue for developing safer and effective cancer treatments.
- Plant-derived compounds may help overcome toxicity and drug resistance associated with synthetic chemotherapy.
- Further research into phytochemicals is crucial for advancing cancer therapy.
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