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Published on: April 14, 2017
Surgical Feasibility of a One-Stage Cell-Based Arthroscopic Procedure for Meniscus Regeneration: A Cadaveric Study
Michella H Hagmeijer1, Lucienne A Vonk1, Jan-Willem Kouwenhoven1
11 Department of Orthopaedics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands.
Impact Statement:
Meniscus injury remains the most common indication for orthopedic surgery, but loss of functioning meniscus tissue is strongly correlated with development of early osteoarthritis. However, current clinical options for tissue engineering of the meniscus are limited. This study demonstrates the feasibility of combining human meniscus cells with mesenchymal stromal cells to enhance a meniscus scaffold for meniscus regeneration in a one-stage solution for partial meniscal deficiency.
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