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Synthetic Methodologies to Gold Nanoshells: An Overview.

Yu-Chen Wang1, Éric Rhéaume2, Frédéric Lesage3,4

  • 1Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, QC H3A 0B8, Canada. yu-chen.wang@mail.mcgill.ca.

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This review covers gold nanoshell synthesis and functionalization for biomedical applications. It highlights reproducible methods for creating tunable nanomaterials for diagnostics and other uses.

Keywords:
cored gold nanoshellsgold nanoshell synthesisgold nanoshellshollow gold nanoshellstemplate galvanic replacement method

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Area of Science:

  • Nanotechnology and Materials Science
  • Biomedical Engineering
  • Chemical Synthesis

Background:

  • Gold nanostructures offer tunable properties for diverse applications, particularly in biomedicine and diagnostics.
  • Gold nanoshells present a versatile platform with advantageous properties for biological applications.
  • Reproducible synthesis and surface functionalization are critical for evaluating gold nano-architectures' efficacy.

Purpose of the Study:

  • To provide an overview of synthetic methodologies for various gold nanoshells.
  • To discuss surface functionalization techniques for gold nanoshells.
  • To summarize characterization methods for assessing gold nanoshell composition.

Main Methods:

  • Review of existing literature on gold nanoshell synthesis.
  • Discussion of various fabrication and chemical manipulation techniques.
  • Summary of surface functionalization and characterization protocols.

Main Results:

  • Diverse synthetic routes for gold nanoshells are available.
  • Surface functionalization allows tailoring of nanomaterial properties.
  • Characterization methods are essential for quality control and performance evaluation.

Conclusions:

  • Gold nanoshells are highly adaptable nanomaterials for biomedical and diagnostic fields.
  • Controlling synthesis and surface chemistry is key to their effective application.
  • Further research into synthesis and functionalization will enhance their utility.