Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.7K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.7K
Mesenchymal Stem Cells01:19

Mesenchymal Stem Cells

5.6K
Mesenchymal stem cells (MSCs) are adult stem cells that can differentiate into most connective tissue cell types, except for hematopoietic cells, depending upon the source of MSCs. For example, bone-marrow-derived MSCs (BM-MSCs) can differentiate into osteocytes, hepatocytes, and pancreatic and neuronal cells. MSCs can be isolated from various sources such as bone marrow, placenta, adipose tissue, teeth, and Wharton’s jelly, a gelatinous substance in the umbilical cord. The ease of their...
5.6K
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

2.1K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
2.1K
Adult Stem Cells01:33

Adult Stem Cells

33.9K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
33.9K
Plant Cells and Tissues02:01

Plant Cells and Tissues

65.7K
Plant tissues are collections of similar cells performing related functions. Different plant tissues will have their own specialized roles and can be combined with other tissues to form organs such as flowers, fruit, stem, and leaves. Two major types of plant tissue include meristematic and permanent tissue.
65.7K
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.4K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Impact of Collection Protocol on the Yield and Purity of Mesenchymal Stem Cell-Derived Extracellular Vesicles Isolated From Serum-Free Media.

Biotechnology journal·2026
Same author

Corrigendum to "Biomimetic bone calcium phosphate-based scaffolds fabricated via ceramic vat photopolymerization: Effect of porosity, sintering temperature, mineralogical phases and trace elements on the osteogenic potential" [Mater. Today Bio 38 (2026) 103074].

Materials today. Bio·2026
Same author

Corrigendum to "Biomimetic bone calcium phosphate-based scaffolds fabricated via ceramic vat photopolymerization: Effect of porosity, sintering temperature, mineralogical phases and trace elements on the osteogenic potential" [Mater. Today Bio 38 (2026) 103074].

Materials today. Bio·2026
Same author

Cu-N-doped graphene/prussian blue interface enables molecularly imprinted electrochemical sensing of L-kynurenine.

Biosensors & bioelectronics·2026
Same author

Pericardial fluid extracellular vesicles enhance angiogenesis and blunt cardiac fibrosis in coronary disease.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Effect of VEGF coating and intra-arterial injection of mesenchymal stem cells on neointima formation after endovascular stenting in a rabbit model.

Journal of neurosurgery·2026
Same journal

RETRACTION: The DNMT1/miR-34a Axis Is Involved in the Stemness of Human Osteosarcoma Cells and Derived Stem-Like Cells.

Stem cells international·2026
Same journal

RETRACTION: Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity.

Stem cells international·2026
Same journal

In Vitro Evaluation of Mechanical Fat Processing Devices: Impact on Adipocytes and Adipose-Derived Stem Cells.

Stem cells international·2026
Same journal

Hyaluronic Acid Hydrogel Inhibits Autophagy Through the miR-181a-5p/ATG5 Molecular Axis to Promote the Adipogenic Differentiation of Adipose-Derived Stem Cells.

Stem cells international·2026
Same journal

RETRACTION: Naringin Stimulates Osteogenic Differentiation of Rat Bone Marrow Stromal Cells via Activation of the Notch Signaling Pathway.

Stem cells international·2026
Same journal

Efficient Derivation and Transcriptional Characterization of Mouse Extra-Embryonic Endoderm Stem Cell Lines Generated by Somatic Cell Nuclear Transfer.

Stem cells international·2026
See all related articles

Related Experiment Video

Updated: Feb 2, 2026

Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats
10:50

Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats

Published on: April 7, 2023

4.2K

Mesenchymal Stem Cell Therapy for Ischemic Tissues.

Kar Wey Yong1,2, Jane Ru Choi3,4, Mehdi Mohammadi2,5

  • 1Pharmaceutical Production Research Facility, Department of Chemical and Petroleum Engineering, Schulich School of Engineering, University of Calgary, 2500 University Drive NW, Calgary, AB, T2N 1N4, Canada.

Stem Cells International
|November 8, 2018
PubMed
Summary
This summary is machine-generated.

Human mesenchymal stem cells (hMSCs) show promise for treating ischemic diseases by reducing inflammation and promoting tissue repair. Further research is needed to overcome clinical challenges for effective hMSC therapy.

More Related Videos

Isolation of Rat Adipose Tissue Mesenchymal Stem Cells for Differentiation into Insulin-producing Cells
08:09

Isolation of Rat Adipose Tissue Mesenchymal Stem Cells for Differentiation into Insulin-producing Cells

Published on: August 29, 2022

8.5K
Technique for Obtaining Mesenchymal Stem Cell from Adipose Tissue and Stromal Vascular Fraction Characterization in Long-Term Cryopreservation
05:57

Technique for Obtaining Mesenchymal Stem Cell from Adipose Tissue and Stromal Vascular Fraction Characterization in Long-Term Cryopreservation

Published on: December 30, 2021

3.9K

Related Experiment Videos

Last Updated: Feb 2, 2026

Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats
10:50

Author Spotlight: Isolation and Identification of Mesenchymal Stem Cells Derived from Adipose Tissue of Sprague Dawley Rats

Published on: April 7, 2023

4.2K
Isolation of Rat Adipose Tissue Mesenchymal Stem Cells for Differentiation into Insulin-producing Cells
08:09

Isolation of Rat Adipose Tissue Mesenchymal Stem Cells for Differentiation into Insulin-producing Cells

Published on: August 29, 2022

8.5K
Technique for Obtaining Mesenchymal Stem Cell from Adipose Tissue and Stromal Vascular Fraction Characterization in Long-Term Cryopreservation
05:57

Technique for Obtaining Mesenchymal Stem Cell from Adipose Tissue and Stromal Vascular Fraction Characterization in Long-Term Cryopreservation

Published on: December 30, 2021

3.9K

Area of Science:

  • Regenerative Medicine
  • Cardiovascular Research
  • Neurology

Background:

  • Ischemic diseases, including myocardial infarction and stroke, pose significant public health burdens.
  • Current treatments for ischemic diseases are often insufficient and carry risks.
  • Human mesenchymal stem cells (hMSCs) offer potential therapeutic benefits due to their regenerative properties.

Purpose of the Study:

  • To review the pathogenesis of ischemic diseases.
  • To discuss the therapeutic potential and mechanisms of hMSCs in treating these conditions.
  • To outline the clinical challenges associated with hMSC therapy.

Main Methods:

  • Literature review of ischemic disease pathogenesis.
  • Analysis of studies on hMSC immunomodulation, angiogenesis, and paracrine effects.
  • Examination of clinical trial data and challenges for hMSC application.

Main Results:

  • hMSCs demonstrate immunomodulatory, angiogenic, and regenerative capabilities.
  • hMSCs secrete bioactive factors that can reduce inflammation and promote tissue repair.
  • Existing research highlights the potential of hMSCs as a cell-based therapy for ischemic conditions.

Conclusions:

  • hMSCs represent a promising therapeutic avenue for ischemic diseases.
  • Further investigation and development are required to address clinical implementation challenges.
  • hMSC therapy holds potential for improving outcomes in patients with myocardial infarction, ischemic stroke, and critical limb ischemia.