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Updated: Feb 2, 2026

Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
Novel key cytokines in allergy: IL-17, IL-22
S Eyerich1, C Traidl-Hoffmann1,2, H Behrendt1
1ZAUM - Zentrum Allergie & Umwelt, Technische Universität und Helmholtz-Zentrum München, Munich, Germany.
Abstract:
The biology of the T cell cytokines Interleukin (IL-)17 and IL-22 has been a main focus in the field of clinical immunology in the last decade. This intensive interest in both cytokines has resulted in almost 5,000 scientific publications (www.pubmed.com) dealing with the molecular structure, extra- and intracellular signaling pathways, specific transcription factors and the function of IL-17 and IL-22. This review article highlights the main findings concerning IL-17 and IL-22 in the last years.
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