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Updated: Feb 2, 2026
A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
Published on: March 17, 2015
Evolutionary Changes in the Content of Dehydrogenase System Metabolites as a Mechanism of Adaptation to Cold in
O N Kolosova1, B M Kershengolts2, N G Solomonov2
1Institute of Biological Problems of Cryolithozone, Siberian Branch, Russian Academy of Sciences, Yakutsk, Russia. kololgonik@gmail.com.
Abstract:
It has been found that the optimal body balance control under the conditions of the adaptation to cold is mostly determined by the ratio of the blood concentrations of endogenous ethanol and acetaldehyde related to the activities of liver alcohol dehydrogenase and aldehyde dehydrogenase in the order of increasing level of adaptation: higher vertebrates unadapted to cold, including human → small animals adapted to cold → large animals adapted to cold native to the North → hibernators, regardless of the species specificity and the environment.
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