Related Experiment Video
Updated: Feb 2, 2026
09:41
Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
12.0K
Relationship between subjective visual vertical and balance in individuals with multiple sclerosis
Brooke N Klatt1, Patrick J Sparto1, Lauren Terhorst2
1Department of Physical Therapy, University of Pittsburgh, Pittsburgh, Pennsylvania.
Summary
Subjective visual vertical (SVV) deviations correlate with poorer balance in multiple sclerosis (MS) patients with cerebellar involvement. This suggests SVV testing could inform physical therapy interventions for MS.
Area of Science:
- Neurology
- Physical Therapy
- Vision Science
Background:
- Subjective visual vertical (SVV) deviations are linked to cerebellar dysfunction in multiple sclerosis (MS).
- MS patients exhibit a higher prevalence of SVV abnormalities, yet this is not routinely assessed in physical therapy evaluations.
- Cerebellar involvement in MS can impact balance and spatial orientation.
Purpose of the Study:
- To investigate the relationship between SVV deviations and balance performance in individuals with MS and cerebellar involvement.
- To determine if SVV testing can predict balance deficits in this population.
- To hypothesize that greater SVV deviations correlate with worse balance outcomes.
Main Methods:
- Twenty participants (15 female, 5 male; mean age 54.5 years) with MS and cerebellar involvement were recruited.
- Computerized SVV testing was performed using rod-only and rod-and-frame conditions, with frame rotation analyzed independently for clockwise (CW) and counterclockwise (CCW) directions.
- Balance was assessed using six functional outcome measures.
Main Results:
- Significant moderate correlations were found between SVV deviations (CCW frame tilt) and all six balance outcomes (Barthel Index, Berg Balance Score, gait velocity, ICARS, SARA, Timed Up and Go).
- The Barthel Index showed a significant moderate correlation with SVV deviations during CW frame tilt.
- Increased SVV deviations, particularly with CCW frame tilt, were associated with worse functional balance outcomes.
Conclusions:
- Individuals with MS experiencing balance impairments may depend more on visual cues for orientation.
- SVV assessment can provide valuable clinical insights for identifying appropriate interventions in MS patients.
- Integrating SVV testing into physical therapy evaluations may enhance the identification of individuals at risk for balance deficits.
Related Concept Videos
02:12Relationship Formation
46.2K
What do you think is the single most influential factor in determining with whom you become friends and whom you form romantic relationships? You might be surprised to learn that the answer is simple: the people with whom you have the most contact. This most important factor is proximity. You are more likely to be friends with people you have regular contact with. For example, there are decades of research that shows that you are more likely to become friends with people who live in your dorm,...
46.2K
02:58Balancing Redox Equations
62.1K
Electrochemistry is the science involved in the interconversion of electrical and chemical reactions. Such reactions are called reduction-oxidation, or redox reactions. These important reactions are defined by changes in oxidation states for one or more reactant elements and include a subset of reactions involving the transfer of electrons between reactant species. Electrochemistry as a field has evolved to yield sufficient insights on the fundamental principles of redox chemistry and multiple...
62.1K
01:28Ending Relationships
189
The dissolution of intimate relationships presents complex emotional and psychological challenges, particularly when emotional bonds are strong, the relationship is long-standing, and perceived alternatives are limited. This distress often intensifies in romantic breakups, where the initiator may experience greater turmoil than the rejected partner. Contributing factors include residual attachment, guilt over causing pain, and uncertainty about how to manage the situation. The stress is further...
189
01:23Vertical Curve: Problem Solving
495
Vertical curves provide the transition between two roadway grades, ensuring safety, comfort, and functionality. Calculating elevations at specific stations along the curve involves several systematic steps based on the curve's geometry and provided design parameters.The vertical curve is defined by its length, grades, Point of Vertical Intersection (P.V.I.) location, and P.V.I. elevation. The stations of the Point of Vertical Curvature (P.V.C.), where the curve begins, and the Point of Vertical...
495
01:30Impact of Individuals on Individuals
382
Human behavior is intricately shaped by social influences that arise from interactions with others in diverse contexts. These influences not only mold beliefs and attitudes but also drive the regulation of behaviors through both direct communication and observational learning. The study of these processes falls within the domain of social psychology, which seeks to understand how individuals are affected by and affect those around them.Mechanisms of Social InfluenceDirect social influence...
382
01:24Introduction to Vertical Curves
592
Vertical curves are parabolic transitions that connect different grades on highways and railroads, ensuring a smooth alignment between back and forward tangents. The back tangent represents the initial grade, while the forward tangent defines the subsequent grade. These curves can be symmetrical, with equal tangent lengths, or nonsymmetrical, with varying lengths. The key points defining a vertical curve include the Point of Vertical Intersection (P.V.I.), where the tangents meet; the Point of...
592