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Updated: Feb 2, 2026

Author Spotlight: Innovative Microneedle-Based Strategies for Enhanced Exosome Delivery and Stability
Published on: July 12, 2024
Exosomes and Exosome-Inspired Vesicles for Targeted Drug Delivery
Sophia G Antimisiaris1,2, Spyridon Mourtas3, Antonia Marazioti4
1Laboratory of Pharmaceutical Technology, Department of Pharmacy, University of Patras, 26504 Rio-Patras, Greece. santimis@upatras.gr.
Abstract:
The similarities between exosomes and liposomes, together with the high organotropism of several types of exosomes, have recently prompted the development of engineered-exosomes or exosome-mimetics, which may be artificial (liposomal) or cell-derived vesicles, as advanced platforms for targeted drug delivery. Here, we provide the current state-of-the-art of using exosome or exosome-inspired systems for drug delivery. We review the various approaches investigated and the shortcomings of each approach. Finally the challenges which have been identified to date in this field are summarized.
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