Related Experiment Video
Updated: Feb 2, 2026

HKUST-1 as a Heterogeneous Catalyst for the Synthesis of Vanillin
Published on: July 23, 2016
A Scandium Arylsulfonate-based Coordination Polymer as a Heterogeneous Catalyst for the Friedel-Crafts Reaction of
Pennapa Tungjiratthitikan1, Hiroshi Furuno2
1Department of Molecular and Material Sciences, Interdisciplinary Graduate School of Engineering Sciences, Kyushu University.
Abstract:
The scandium sulfonate-based coordination polymer Sc2(BPDS)3, which is easily prepared by mixing scandium triisopropoxides and biphenyl-4,4'-disulfonic acid (BPDSA), is an air-stable and storable solid that effectively catalyzes the Friedel-Crafts reaction of indoles with aromatic aldehydes under heterogeneous conditions to afford various aryl(diindolyl)methanes. The catalyst can be reused without significant loss of activity after separation from the reaction mixture by simple centrifugation followed by drying.
Related Concept Videos
Limitations of Friedel–Crafts Reactions
Electrophilic Aromatic Substitution: Friedel–Crafts Alkylation of Benzene
Electrophilic Aromatic Substitution: Friedel–Crafts Acylation of Benzene
Polymers
Coordination Number and Geometry
Acids, Bases and Neutralization Reactions

