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Updated: Feb 2, 2026

Absolute Quantum Yield Measurement of Powder Samples
Published on: May 12, 2012
Camouflaged Nanosilver with Excitation Wavelength Dependent High Quantum Yield for Targeted Theranostic
Agnishwar Girigoswami1, Wafic Yassine2, Palani Sharmiladevi2
1Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute (CHRI), Chettinad Academy of Research & Education (CARE), Kelambakkam, Chennai, 603 103, India. agnishwarg@gmail.com.
Abstract:
The present study shows the thorough investigations on optical properties and hydrodynamic diameters of glutathione (GSH) stabilized nanosilver clusters (AgNC) at different stages of synthesis and engineering for the optimized absolute quantum yield to generate fluorescent images of Dalton Lymphoma Ascites (DLA) tumour bearing mice. The initial increment of quantum yield was wavelength dependent and finally it became 0.509 which was due to the camouflaging or entrapment of AgNC in macrophages membranes. The potentiality of macrophages membrane camouflaged silver nanoclusters (AgM) was reflected in the cell viability assay and confocal based live dead cell assay where the AgM has better cell killing effect compared to AgNC with reduced dosage and in vivo mice imaging generated the clear visualization at the tumour sites. Therefore, from the present study, it can be considered that the camouflaged nanosilver can be used for targeted theranostic applications.
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