Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Review and Preview01:10

Review and Preview

8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview01:13

Review and Preview

11.3K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.3K
Subatomic Particles03:37

Subatomic Particles

113.1K
Dalton was only partially correct about the particles that make up matter. All matter is composed of atoms, and atoms are composed of three smaller subatomic particles: protons, neutrons, and electrons. These three particles account for the mass and the charge of an atom.
113.1K
The Nucleosome Core Particle02:10

The Nucleosome Core Particle

14.5K
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
The paradox
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their main responsibility is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. While on the other hand, they must allow polymerase enzymes to access DNA...
14.5K
The Nucleosome Core Particle01:12

The Nucleosome Core Particle

2.4K
Nucleosomes are the DNA-histone complex, where the DNA strand is wound around the histone core. The histone core is an octamer containing two copies of H2A, H2B, H3, and H4 histone proteins.
Nucleosomes, paradoxically, perform two opposite functions simultaneously. On the one hand, their primary aim is to protect the delicate DNA strands from physical damage and help achieve a higher compaction ratio. On the other hand, they must allow polymerase enzymes to access histone-bound DNA during...
2.4K
Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision02:43

Basic Postulates of Kinetic Molecular Theory: Particle Size, Energy, and Collision

37.8K
The ideal-gas equation, which is empirical, describes the behavior of gases by establishing relationships between their macroscopic properties. For example, Charles’ law states that volume and temperature are directly related. Gases, therefore, expand when heated at constant pressure. Although gas laws explain how the macroscopic properties change relative to one another, it does not explain the rationale behind it.
37.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensor-derived multidimensional gait domains mediate the association between intrinsic capacity impairment and fall risk in community-dwelling older adults: a cross-sectional study.

The journal of nutrition, health & aging·2026
Same author

Associations of adiponectin, leptin, and the adiponectin-to-leptin ratio with sarcopenia in older adults with cardiovascular-kidney-metabolic syndrome.

The journal of nutrition, health & aging·2026
Same author

Brain-Derived Neurotrophic Factor, Sarcopenia and Digital Gait Characteristics in Older Adults: Insights Into the Brain-Muscle Axis.

Journal of cachexia, sarcopenia and muscle·2026
Same author

Trefoil polymers from a knotted synthon.

Nature chemistry·2026
Same author

Engineering Pseudomonas protegens as a Targeted Antifungal-Effector Delivery Chassis via Heterologous Type III Secretion System Reconstitution.

Microbial biotechnology·2026
Same author

Associations of insulin-like growth factor-1 with gait vigor, symmetry, and stability metrics measured by wearable sensors in older adults.

BMC geriatrics·2026

Related Experiment Video

Updated: Feb 2, 2026

Assessment of GFP Expression and Viability Using the Tali Image-Based Cytometer
10:58

Assessment of GFP Expression and Viability Using the Tali Image-Based Cytometer

Published on: November 17, 2011

21.7K

Optofluidic Device Based Microflow Cytometers for Particle/Cell Detection: A Review.

Yushan Zhang1, Benjamin R Watts2, Tianyi Guo3

  • 1School of Biomedical Engineering, McMaster University, 1280 Main Street West, Hamilton, ON L8S 4L8, Canada. zhang749@mcmaster.ca.

Micromachines
|November 9, 2018
PubMed
Summary

Optofluidic microflow cytometers integrate optics and microfluidics for advanced diagnostics. These devices offer high sensitivity and on-chip alignment, improving cellular analysis and point-of-care testing.

Keywords:
microfabricationmicroflow cytometermicrofluidicsoptofluidic device

More Related Videos

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
07:15

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform

Published on: May 18, 2021

3.5K
Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children
06:22

Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children

Published on: February 10, 2023

1.3K

Related Experiment Videos

Last Updated: Feb 2, 2026

Assessment of GFP Expression and Viability Using the Tali Image-Based Cytometer
10:58

Assessment of GFP Expression and Viability Using the Tali Image-Based Cytometer

Published on: November 17, 2011

21.7K
Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform
07:15

Single-Cell Characterization of Calcium Influx and HIV-1 Infection using a Multiparameter Optofluidic Platform

Published on: May 18, 2021

3.5K
Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children
06:22

Standardization of Transfer across Labs between Flow Cytometers for Detection of Lymphocytes in Japanese Encephalitis Vaccinated Children

Published on: February 10, 2023

1.3K

Area of Science:

  • Optofluidics
  • Microfluidics
  • Biomedical Engineering

Background:

  • Conventional microfluidic devices lack integrated optical capabilities.
  • Optofluidics combines micro-optical and microfluidic components for enhanced functionality.
  • On-chip integration offers advantages like optical beam shaping and built-in alignment.

Purpose of the Study:

  • To review the principles and recent developments in optofluidic microflow cytometers.
  • To discuss key techniques enabling optofluidic microflow cytometer performance.
  • To highlight the role of 3D microfabrication in advancing these devices.

Main Methods:

  • Detailed discussion of flow control techniques.
  • Analysis of light guiding and collecting methods.
  • Review of data collection and analysis strategies in optofluidic systems.

Main Results:

  • Optofluidic microflow cytometers demonstrate high sensitivity and built-in optical alignment.
  • Applications span point-of-care diagnostics, cellular immunophenotyping, rare cell analysis, genomics, and analytical chemistry.
  • 3D microfabrication techniques facilitate the miniaturization and integration of optofluidic systems.

Conclusions:

  • The integration of microfluidics and optics drives innovation in microflow cytometry.
  • Advancements in fabrication and system integration enhance device performance.
  • Optofluidic microflow cytometers show significant potential for diverse analytical applications.