Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paraneoplastic syndromes.

D C Ihde

    Hospital Practice (Office Ed.)
    |August 15, 1987
    PubMed
    Summary

    Paraneoplastic syndromes, though poorly understood, are linked to cancer and can aid diagnosis or treatment monitoring. Studying them offers insights into cancer mechanisms and patient palliation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Paclitaxel/ifosfamide or navelbine/ifosfamide chemotherapy for advanced non-small cell lung cancer: CALGB 9532.

    Lung cancer (Amsterdam, Netherlands)·2000
    Same author

    Small-cell lung cancer: treatment progress and prospects.

    Oncology (Williston Park, N.Y.)·1998
    Same author

    Alternating MOPP and ABVD chemotherapy plus mantle-field radiation therapy in patients with massive mediastinal Hodgkin's disease.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·1997
    Same author

    Outcome of patients with small-cell lung cancer during 20 years of clinical research at the US National Cancer Institute.

    Mayo Clinic proceedings·1997
    Same author

    Survival of patients with limited-stage small cell lung cancer treated with individualized chemotherapy selected by in vitro drug sensitivity testing.

    Clinical cancer research : an official journal of the American Association for Cancer Research·1997
    Same author

    Practical issues in the management of the patient with small cell lung cancer.

    Chest surgery clinics of North America·1997

    Area of Science:

    • Oncology
    • Neurology
    • Immunology

    Background:

    • Paraneoplastic syndromes present diverse, often poorly understood, manifestations in cancer patients.
    • Common symptoms like anorexia-cachexia or fever are frequently not fully explained.
    • While affecting a minority, these syndromes are strongly associated with cancer.

    Purpose of the Study:

    • To review the clinical significance and potential mechanisms of paraneoplastic syndromes.
    • To explore their role in cancer diagnosis, treatment monitoring, and palliation.
    • To understand how studying these syndromes can illuminate broader cancer biology.

    Main Methods:

    • Review of existing literature on paraneoplastic syndromes.
    • Analysis of syndromes clearly or strongly associated with cancer.
    • Discussion of potential etiologic mechanisms, including tumor-produced substances and autoimmune phenomena.

    Main Results:

    • Paraneoplastic syndromes can be crucial for early cancer diagnosis and assessing treatment response.
    • They may be mistaken for metastatic disease, highlighting the need for accurate differentiation.
    • Understanding these syndromes can lead to significant clinical palliation for affected patients.

    Conclusions:

    • The study of paraneoplastic syndromes provides valuable insights into unexplained cancer-related abnormalities.
    • Tumor-produced substances and autoimmune responses are key mechanisms.
    • Further research into paraneoplastic syndromes may enhance understanding of tumor growth and regulation.

    Related Experiment Videos