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Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells
Published on: May 4, 2018
Could nanotechnology make vitamin E therapeutically effective?
Tetsuya Tamura1, Gail Otulakowski1, Brian P Kavanagh1
1Program in Translational Medicine, The Research Institute, and the Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto , Toronto , Canada.
Abstract:
Vitamin E (VitE) has important antioxidant and anti-inflammatory effects and is necessary for normal physiological function. α-Tocopherol (α-T), the predominant form of VitE in human tissues, has been extensively studied. Other VitE forms, particularly γ-tocopherol (γ-T), are also potent bioactive molecules. The effects are complex, involving both reactive oxygen and nitrogen species, but trials of VitE have been generally negative. We propose that a nanoparticle approach to delivery of VitE might provide effective delivery and therapeutic effect.
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