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Updated: Feb 2, 2026

Epidural Intracranial Pressure Measurement in Rats Using a Fiber-optic Pressure Transducer
Published on: April 25, 2012
The Impact of Head-of-Bed Positioning and Transducer Location on Cerebral Perfusion Pressure Measurement
Molly McNett1, Sarah Livesay, Susan Yeager
1Sarah Livesay, DNP ACNP FNCS, is Associate Professor, Rush University, Chicago, IL. Susan Yeager, MS ACNP FNCS, is Nurse Practitioner Lead, Wexner Medical Center, The Ohio State University, Columbus, OH. Cristina Moran, MSN RN CCRN, is Clinical Nurse, The MetroHealth System, Cleveland, OH. Erin Supan, MSN RN, is Clinical Nurse Specialist, Neurosciences, University Hospitals Cleveland Medical Center, Cleveland, OH. Stefany Ortega, MSc RN, is Assistant Professor, Universidad del Norte, Barranquilla, Colombia. DaiWai M. Olson, PhD RN CCRN FNCS, is Professor of Neurosurgery and Neurotherapeutics, University of Texas Southwestern, Dallas, TX.
Introduction:
Head-of-bed (HOB) elevation is the standard of care for patients with intracranial pressure monitoring at risk for intracranial hypertension. Measurement of cerebral perfusion pressure (CPP) based on HOB elevation and arterial transducer position has not been adequately studied.
Methods:
This is a planned secondary analysis of prospectively collected data in which paired, serial arterial blood pressure (ABP), intracranial pressure, and CPP measures were obtained once per day for 3 days, with measures leveled at the tragus (Tg) and the phlebostatic axis (PA). The HOB position was recorded for all paired readings.
Results:
From 136 subjects, ABP and CPP values were lower when the transducer was leveled at the Tg, compared with the PA (P < .001); these differences persisted regardless of HOB position.
Conclusion:
The difference in CPP when ABP is referenced at the Tg versus PA is not consistently attributed to HOB elevation.
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