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Dual functionality of lamprey VLRB C-terminus (LC) for multimerization and cell surface display

Jung Seok Lee1, Jaesung Kim1, Se Pyeong Im1

  • 1Laboratory of Aquatic Animal Diseases, College of Veterinary Medicine, Gyeongsang National University 900 Gajwadong, Jinju, Gyeongnam, 660-701, South Korea.

Molecular Immunology
|November 9, 2018
PubMed
Summary

Lamprey variable lymphocyte receptors B (VLRB) can be engineered for secretion or membrane anchoring. The C-terminus of VLRB (LC) shows potential as a fusion partner for multimerization and antibody display technology.

Keywords:
Antibody displaying systemGPI signal domainLampreyMultimerization domainVariable lymphocyte B (VLRB)

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