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Detection of Protein S-Acylation using Acyl-Resin Assisted Capture
Published on: April 10, 2020
Acyl atractyligenin and carboxyatractyligenin glycosides from Antennaria rosea subsp. confinis
Yangyang Xiao1, Ling Lv1, Ping Gou2
1Key Laboratory of South China Agricultural Plant Molecular Analysis and Genetic Improvement, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, China; University of Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
Eight previously undescribed acyl atractyligenin and carboxyatractyligenin glycosides were isolated from whole Antennaria rosea subsp. confinis (Greene) R. J. Bayer (Compositae) [syn. Leontopodium leontopodioides (Willd.) Beauv. (Asteraceae)] plants and their structures were determined by spectroscopic and chemical methods. The compounds were trivially named leontopodiosides F-M. Seven of the compounds showed potent in vitro inhibitory activity toward pancreatic lipase with IC50 values ranging from 3.4 to 52.5 μM, suggesting that they participate in the previously observed effect this plant has in reducing triglyceride absorption in rats.
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