Carotid Revascularization with and without the Use of an Embolic Protection Device: A Single-Center Experience from Pakistan
Related Experiment Video
Updated: Feb 2, 2026

Laparoscopic Anterior Right Hepatectomy: A Single-Center Experience
Published on: December 4, 2023
Qasim Bashir1,2, Ammad Anwar Baig3
1Department of Neurointervention, Bahria Town Hospital, Lahore, Pakistan.
Insights
Carotid artery stenting without embolic protection devices (EPD) is safe and effective for patients with carotid disease. This approach is also cost-effective, reducing unnecessary disposable use in experienced hands.
Area of Science:
- Vascular Surgery
- Interventional Cardiology
- Neurology
Background:
- Carotid artery stenting is a common procedure for treating carotid artery disease.
- The use of embolic protection devices (EPD) during stenting is debated.
- Assessing the safety and efficacy of stenting with and without EPD is crucial for patient outcomes.
Purpose of the Study:
- To evaluate the safety and clinical efficacy of carotid artery stenting (CAS) with and without embolic protection devices (EPD).
- To compare outcomes in both symptomatic and asymptomatic patients with carotid disease.
Main Methods:
- Retrospective review of 55 carotid disease cases undergoing stenting/angioplasty.
- Inclusion criteria based on degree of carotid artery occlusion via digital subtraction angiography (DSA), ultrasound, CTA, and MRA.
- Primary endpoints included periprocedural stroke, myocardial infarction, death, and long-term ipsilateral stroke.
Main Results:
- 92.7% of patients were symptomatic with a mean stenosis of 80.1%.
- EPD was used selectively in 20% of cases.
- A low rate of minor stroke (1.8%) was observed with EPD use; no myocardial infarction or mortality. No strokes occurred during follow-up.
Conclusions:
- Carotid revascularization with stenting and angioplasty without EPD is safe and effective in experienced centers.
- This approach is cost-effective by minimizing the use of disposable devices.
- Further large-scale randomized trials are warranted to confirm these findings.
Background:
To assess the safety and clinical efficacy of carotid artery stenting with and without an embolic protection device (EPD) in both symptomatic and asymptomatic carotid disease cases.
Methods:
Retrospective data of 55 symptomatic (≥50% occlusion by digital subtraction angiography [DSA], ≥70% by ultrasound, computed tomography angiography [CTA], and magnetic resonance angiography [MRA]) and asymptomatic (≥60% by DSA, ≥70% by ultrasound, ≥80% by CTA and MRA) carotid disease cases undergoing carotid stenting/angioplasty revascularization from February 2014 to October 2017 was reviewed. All symptomatic patients either experienced recurrent transient ischemic attacks or one or more stroke attacks. An EPD protocol was designed for its selective use based on plaque morphologies and working diameters. The primary end points at 30 days of follow-up were a periprocedural incidence of any stroke, myocardial infarction or death, and ipsilateral stroke during the follow-up period.
Results:
Of the 55 cases, 39 were males and 16 females; mean age was 64.8 years. Fifty-one patients (92.7%) were symptomatic, with a mean stenosis of 80.1%. EPD was used in only 11 cases (20%). Minor stroke rate during the first 30 postoperative days was 1.8% (1 case) with EPD; no myocardial infarction or mortality. No stroke occurred during the median 1.5 years' follow-up.
Conclusion:
Based on our single-center experience and findings of a relatively small sample size, carotid revascularization with stenting and angioplasty without EPD in experienced hands was found to be safe and efficacious. In addition, it proves cost-effective for patients by limiting the use of unnecessary disposables. These results are comparable to those reported in major trials and are well within the complication thresholds suggested in current guidelines. These results also show promise and illustrate the need for a larger, randomized controlled trial in order to thoroughly address this aspect of carotid revascularization.
More Related Videos
Related Concept Videos
Pulmonary Embolism I: Introduction
Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...
Center of Gravity
Center of Gravity
To determine its location, the principle of moments can be utilized by dividing the object into...
Center of Mass
The knowledge of the center of mass can also help us to describe and predict the motion of objects. For example, when a ball is thrown...
Protection of Alcohols
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...

