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Related Concept Videos

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An experiment is a planned activity carried out under controlled conditions. The purpose of an experiment is to investigate the relationship between two variables. When one variable causes change in another, we call the first variable the explanatory or independent variable. The affected variable is called the response or dependent variable. In a randomized experiment, the researcher manipulates values of the explanatory variable and measures the resulting changes in the response variable. The...
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Related Experiment Video

Updated: Feb 2, 2026

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
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Multicenter Experience with Stenting for Symptomatic Carotid Web.

Diogo C Haussen1, Jonathan A Grossberg1, Sebastian Koch2

  • 1Emory University/Grady Memorial Hospital, Atlanta, Georgia, USA.

Interventional Neurology
|November 10, 2018
PubMed
Summary
This summary is machine-generated.

Stenting carotid webs (CaW), a cause of stroke, is a safe and effective treatment. This multicenter study shows no recurrent cerebrovascular events after stenting, with high functional independence.

Keywords:
Carotid webFibromuscular dysplasiaStentStroke

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Area of Science:

  • Vascular Neurology
  • Interventional Neuroradiology
  • Cerebrovascular Disease

Background:

  • Carotid web (CaW) is a posterior internal carotid bulb lesion, an intimal fibromuscular dysplasia variant.
  • CaW is linked to recurrent strokes and traditionally treated with surgical excision.
  • This study evaluates stenting for symptomatic CaW across multiple stroke centers.

Purpose of the Study:

  • To assess the safety and efficacy of carotid stenting for symptomatic carotid webs.
  • To report multicenter outcomes of patients treated with stenting for CaW.

Main Methods:

  • Retrospective review of 24 patients with symptomatic CaW treated with stenting at 5 stroke centers.
  • Symptomatic CaW diagnosed via CTA and conventional angiography in patients with negative stroke workup.
  • Patients received dual antiplatelets; stenting performed median 9 days post-event.

Main Results:

  • 83% of patients experienced stroke, 17% TIA; median age 47, 71% Black, 58% female.
  • No periprocedural events except 2 cases of asymptomatic hypotension/bradycardia.
  • Median 12-month follow-up showed no new cerebrovascular events; 91% achieved 90-day functional independence. No stenosis on follow-up imaging.

Conclusions:

  • Carotid stenting is a safe and effective alternative to surgical resection for symptomatic CaW.
  • Further research is needed to confirm these findings.
  • Stenting offers a viable treatment option for CaW-related cerebrovascular events.