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Standard Operating Procedure for Lyssavirus Surveillance of the Bat Population in Taiwan
Published on: August 27, 2019
Serological evidence of human infection by bat orthoreovirus in Singapore
Anna Uehara1, Chee Wah Tan1, Shailendra Mani1
1Programme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Abstract:
To determine whether Pteropine orthoreovirus (PRV) exposure has occurred in Singapore, we tested 856 individuals from an existing serum panel collected from 2005-2013. After an initial screen with luciferase immunoprecipitation system and secondary confirmation with virus neutralization test, we identified at least seven individuals with specific antibodies against PRV in both assays. Our findings confirm that PRV spillover into human populations is relatively common in this region of the world.
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