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[Proton therapy: clinico-methodological aspects, treatment results]
Meditsinskaia Radiologiia
|August 1, 1987
Summary
Proton beam therapy demonstrated high efficacy and safety in treating various conditions, including pituitary adenomas and arteriovenous malformations, with prolonged remission and successful exclusion of aneurysms observed in a significant number of patients.
Area of Science:
- Radiation Oncology
- Neurosurgery
- Endocrinology
Context:
- Proton beam therapy (PBT) is an advanced radiation technique.
- The study retrospectively analyzed PBT outcomes from 1975-1986.
- A cohort of 457 patients with diverse conditions received treatment.
Purpose:
- To evaluate the efficacy and safety of proton beam therapy.
- To assess treatment outcomes for specific conditions including pituitary adenomas and arteriovenous malformations.
- To report long-term remission and radiological outcomes.
Summary:
- Proton beam therapy was administered to 457 patients with conditions such as pituitary adenomas, arteriovenous malformations, and various cancers.
- Prolonged remission rates of 75-90% were observed in patients with pituitary adenomas.
- Angiography confirmed complete aneurysm exclusion in nearly 50% of arteriovenous malformation patients after 2 years.
Impact:
- PBT shows significant promise for managing complex neurological and oncological conditions.
- The findings support PBT as a safe and effective therapeutic modality.
- This study provides valuable long-term data on PBT outcomes.