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Related Experiment Videos

[Fractionated proton radiotherapy].

M Austin-Seymour, J E Munzenrider, L Verhey

    Meditsinskaia Radiologiia
    |August 1, 1987
    PubMed
    Summary
    This summary is machine-generated.

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    The relative costs of proton and X-ray radiation therapy.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2003

    Proton beam therapy, initiated in 1974, has treated over 1300 patients for various cancers, including ocular melanoma and skull base tumors. Advanced techniques ensure precise beam delivery for effective cancer treatment.

    Area of Science:

    • Medical physics
    • Radiation oncology
    • Particle therapy

    Context:

    • Proton beam therapy research began at Harvard University's Cyclotron Laboratory in 1974.
    • Utilized a 160 MeV proton beam for fractionated irradiation.
    • Treated a diverse patient cohort including uveal melanoma, skull base tumors, and sarcomas.

    Purpose:

    • To investigate the efficacy and application of proton beam therapy for various cancers.
    • To develop and implement advanced techniques for precise radiation delivery.
    • To evaluate outcomes for specific tumor types like ocular melanoma and chordoma.

    Summary:

    • Over 1331 patients received proton beam therapy by June 1986.
    • Computer-assisted 3D design and heterogeneity calculations were employed for beam targeting.

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  • Therapy was administered as a standalone treatment or combined with conventional radiotherapy.
  • Key areas of focus included ocular melanoma, skull base chordoma/chondrosarcoma, and paraspinal sarcomas.

    • Impact:

    • Demonstrated the feasibility and application of proton beam therapy for challenging cancers.
    • Highlighted the potential of proton therapy for ocular melanoma and skull base tumors.
    • Paved the way for further investigations into proton beam therapy for malignant meningioma and metastatic disease.