Sentinel lymph node biopsy in porocarcinoma: A case reports

Area of Science:

• Dermatology
• Surgical Oncology
• Pathology

Background:

• Eccrine porocarcinoma (EPC) is a rare, slow-growing sweat gland carcinoma.
• Clinical presentation can mimic benign or malignant skin lesions, necessitating histological confirmation.
• Standard treatment involves surgical excision, but the role of sentinel lymph node biopsy (SNLB) is debated.

Purpose of the Study:

• To report two cases of EPC of the lower limbs.
• To evaluate the efficacy of surgical excision combined with SNLB in managing EPC.
• To discuss the potential utility of SNLB in staging and diagnosis of EPC.

Main Methods:

• Two female patients with lower limb EPC underwent wide surgical excision and SNLB.
• Clinical and pathological data were reviewed.
• A 6-month follow-up was conducted for both patients.

Main Results:

• Both patients achieved disease-free status at 6 months post-treatment.
• Surgical excision provided clear margins.
• SNLB was performed in conjunction with excision.

Conclusions:

• EPC is a rare cutaneous malignancy that must be considered in the differential diagnosis of skin lesions.
• Surgical excision is the established treatment for EPC.
• SNLB may offer benefits for staging and diagnosis, despite its controversial role.