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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Myasthenia gravis is an autoimmune condition affecting neuromuscular transmission, causing generalized weakness in skeletal muscles. Initial diagnoses rely on patients' signs, symptoms, and medical history. The challenge lies in distinguishing myasthenia from other muscular dystrophies. An important diagnostic feature is the significant improvement of symptoms after administering anticholinesterase inhibitors.
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Related Experiment Video

Updated: Feb 2, 2026

Doppler Optical Coherence Tomography of Retinal Circulation
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[Optical coherence tomography angiography: Value for glaucoma diagnostics].

M Alnawaiseh1, L Lahme2, N Eter2

  • 1Klinik für Augenheilkunde, Universitätsklinikum Münster, Domagkstr. 15, 48149, Münster, Deutschland. maged.alnawaiseh@ukmuenster.de.

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|November 11, 2018
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography angiography (OCTA) is a noninvasive tool that quantifies retinal blood flow in glaucoma patients. Reduced flow density in OCTA correlates with glaucoma damage, showing diagnostic potential.

Keywords:
Flow densityFoveal avascular zoneGlaucomaOptical coherence tomography angiographyReproducibility

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Area of Science:

  • Ophthalmology
  • Medical Imaging
  • Glaucoma Research

Background:

  • Optical coherence tomography angiography (OCTA) is a novel noninvasive imaging technique.
  • OCTA allows for quantitative evaluation of retinal and optic nerve head (ONH) perfusion.
  • This review summarizes OCTA's application and findings in glaucoma patients.

Purpose of the Study:

  • To review the principles and applications of OCTA in glaucoma.
  • To summarize current knowledge on OCTA in glaucoma patient diagnostics.
  • To assess the diagnostic potential of OCTA for glaucoma management.

Main Methods:

  • Selective literature search.
  • Analysis of own data.
  • Review of quantitative OCTA parameters and their correlation with glaucoma damage.

Main Results:

  • Quantitative OCTA parameters demonstrate good reproducibility in glaucoma patients.
  • Glaucoma patients exhibit reduced flow density (FD) in the ONH and macula compared to healthy controls.
  • Reduced FD correlates with functional and structural glaucoma damage, showing good, though not superior, diagnostic power compared to structural parameters.

Conclusions:

  • OCTA is a noninvasive, rapid, and reproducible imaging method.
  • Initial studies indicate high diagnostic potential for OCTA in glaucoma.
  • OCTA may become an integral part of future clinical glaucoma management.