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Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry
Published on: March 29, 2018
Common Cell Lines Used to Study Bone Morphogenetic Proteins (BMPs)
Jessica Ann Cottrell1, Donya Burgess2, Sarah Michaels2
1Biological Sciences, Seton Hall University, South Orange, NJ, USA. Jessica.cottrell@shu.edu.
Abstract:
Many research methods exist to elucidate the functions of BMPs during osteogenesis. This chapter briefly reviews common immortalized mesenchymal cell types used to measure the efficacy of osteogenic factors like BMP-2. Detailed information regarding media and culture conditions are provided. Parameters relevant to experimental reproducibility and cell line authentication are discussed.
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