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Ozone therapy for low back pain. A systematic review.
Ozone therapy may improve pain and function for low back pain due to lumbar disc herniation, but evidence is limited. More high-quality studies are needed to confirm its effectiveness and safety.
Area of Science:
- Pain Management
- Regenerative Medicine
- Spinal Disorders
Background:
- Low back pain from lumbar disc herniation significantly impacts quality of life and incurs economic costs.
- Patients unresponsive to conservative treatments explore alternative and minimally invasive options.
- Ozone therapy is investigated for its potential analgesic and anti-inflammatory properties in managing back pain.
Purpose of the Study:
- To systematically review the efficacy and safety of ozone therapy for low back pain in patients with lumbar disc herniation.
Main Methods:
- A systematic search of Pubmed and Scopus was conducted.
- Included studies were original, English-written, human-based, and compared ozone therapy against non-ozone interventions for lumbar disc herniation.
- Seven studies met the inclusion criteria after a rigorous selection process.
Main Results:
- Most studies indicated that ozone therapy yielded similar or superior outcomes compared to control interventions.
- One study showed comparable results for ozone therapy combined with physical therapy versus physical therapy alone.
- Adverse effects were infrequently reported and not significantly different between groups in the limited studies that assessed them.
Conclusions:
- Current evidence for ozone therapy in low back pain due to disc herniation is based on a small number of low-quality studies.
- While preliminary results suggest pain and functional improvements, potential complications are underreported.
- Further rigorous research is essential to establish the definitive role of ozone therapy in managing low back pain.
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