Related Experiment Video
Updated: Feb 2, 2026

Author Spotlight: Enhanced Method for Evaluating Analgesic Effects — Dual Hind Paw Carrageenan Injection in Mice
Published on: November 15, 2024
Anti-inflammatory and analgesic activity of Habbe Gule Aakh, A polyherbal Unani formulation in animal models
B Ganga1, Abdul Wadud1, Nasreen Jahan1
1Department of Ilmul Advia (Pharmacology), National Institute of Unani Medicine, Bengaluru, India.
Background:
Habbe Gule Aakh is extensively used in Unani medicine for anti-inflammatory and analgesic activity.
Objective:
To evaluate anti-inflammatory and analgesic effects of Habbe Gule Aakh on Wistar rats and Swiss mice of either sex.
Materials And Methods:
The study was carried out in Wistar rats for anti-inflammatory activity while Swiss mice were used for analgesic activity. In both the tests animals were divided into five groups of six animals each which served as control, standard and test groups A, B and C. For anti-inflammatory activity, method reported by Amman was followed. For analgesic activity, Koster's protocol was adapted.
Results:
Significant (P < 0.01) reduction in the paw volume was noted in all the test groups but less than the standard drug. Mean writhes of group B and C reduced significantly (P < 0.01) demonstrating analgesic effect.
Conclusion:
The study validated the claim of Unani medicine of use of Habbe Gule Aakh in inflammation and pain. Further, phytochemical studies are needed to know the exact mechanism of action of this formulation.
Related Concept Videos
Opioid Analgesics: Morphine and Other Natural Cogeners
Inflammatory Response
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
Cartesian Form for Vector Formulation
Resultant Moment: Vector Formulation
The resultant moment of a system of forces can be calculated through vector formulation. For example, if we consider...

