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Glass-ceramics for cancer treatment: So close, or yet so far?

Marta Miola1, Yousef Pakzad2, Sara Banijamali3

  • 1Department of Applied Science and Technology, Politecnico di Torino, C.so Duca Degli Abruzzi 24, 10129 Torino, Italy.

Acta Biomaterialia
|November 12, 2018
PubMed

Insights

Glass-ceramics show promise for cancer treatment, moving beyond bone regeneration. Further research is needed to unlock their full potential in clinical cancer therapy applications.

Area of Science:

  • Biomaterials Science
  • Oncology
  • Materials Chemistry

Background:

  • Glass-ceramics, initially researched for bone regeneration, are emerging as promising biomaterials for cancer treatment.
  • Despite growing research, the full potential of glass-ceramics in cancer therapy remains largely untapped.
  • Advancements in magnetic bioactive glass-ceramics and mesoporous bioactive glasses suggest significant future developments.

Purpose of the Study:

  • To review the current research developments in the application of glass-ceramics for cancer treatment.
  • To highlight the current status and explore future advances in this field.
  • To systematically review magnetic bioactive glass-ceramics and mesoporous bioactive glasses for cancer therapy.

Main Methods:

  • Literature review of existing research on glass-ceramics in cancer treatment.
  • Analysis of current products and recent developments in the field.
  • Focus on magnetic bioactive and mesoporous bioactive glass-ceramics.

Main Results:

  • Research activity in glass-ceramics for cancer treatment is significantly increasing.
  • Magnetic bioactive glass-ceramics and mesoporous bioactive glasses are identified as key areas for future progress.
  • The clinical application of glass-ceramics in cancer therapy requires further investigation and answers to critical questions.

Conclusions:

  • Glass-ceramics hold revolutionary potential for cancer treatment, though clinical application requires further development.
  • Magnetic bioactive and mesoporous bioactive glass-ceramics represent promising avenues for future cancer therapies.
  • This review addresses the current state-of-the-art and future prospects, filling a gap in systematic reviews on these specific materials for cancer treatment.
Keywords:
Bioactive glassBiomaterialsCancerFerrimagnetismGlass-ceramicHyperthermiaMagnetite

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