[ECG pearl: the Brugada sign. Case report]

Area of Science:

• Cardiology
• Electrophysiology
• Genetics

Background:

• Brugada syndrome is an inherited cardiac arrhythmia characterized by specific electrocardiogram (ECG) abnormalities.
• It is associated with an increased risk of sudden cardiac death, particularly in individuals of Asian descent.
• Palpitations can be a presenting symptom, necessitating thorough cardiac evaluation.

Observation:

• A case study involving an Asian patient presenting with palpitations.
• Electrocardiogram (ECG) revealed a coved-type Brugada pattern.
• The ECG also showed QRS-fragmentations, a less common but significant finding.

Findings:

• The patient exhibited a coved-type Brugada pattern on ECG, indicative of the syndrome.
• The presence of QRS-fragmentations alongside the Brugada pattern requires careful interpretation.
• This case highlights the variability in ECG manifestations of Brugada syndrome.

Implications:

• Emphasizes the importance of early recognition of Brugada syndrome based on ECG findings.
• Underscores the critical role of risk stratification in managing patients diagnosed with Brugada syndrome.
• Suggests that QRS-fragmentations may be an additional marker to consider in Brugada syndrome diagnosis and risk assessment.