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Intrathecal application of drugs for muscle hypertonia
1Neurosurgical Department, University of Zürich, Switzerland.
Scandinavian Journal of Rehabilitation Medicine. Supplement
|January 1, 1988
Abstract:
The literature regarding the intrathecal use of morphine, baclofen, and midazolam to treat spasticity is reviewed. Nine patients with significant spasticity due to different etiologies were treated. Morphine and midazolam decreased spasticity but did not change the patient's functional status. Baclofen improved patient status, but was associated with significant CNS depression in two cases.