Pregnancy Check Point for Diagnosis of CKD in Developing Countries

Area of Science:

• Nephrology
• Obstetrics
• Public Health

Background:

• Chronic kidney disease (CKD) poses significant risks to maternal and fetal health during pregnancy.
• Early specialist intervention for pregnant individuals with CKD is crucial for optimizing outcomes.

Purpose of the Study:

• To assess the impact of CKD detection during pregnancy on maternal and fetal health.
• To evaluate the outcomes of planned versus unplanned pregnancies in women with CKD.

Main Methods:

• Retrospective analysis of 465 pregnant individuals' renal status.
• Comparison of outcomes between those unaware of renal illness and those under regular follow-up.
• Evaluation of factors like preeclampsia, renal function decline, and fetal birth weight.

Main Results:

• Nearly half of the evaluated pregnancies involved individuals with reduced Glomerular Filtration Rate (GFR < 60 ml/min).
• Unplanned pregnancies showed significantly higher rates of preeclampsia (47.5%) and adverse fetal outcomes, including low birth weight, compared to planned pregnancies (17.6%).
• Worsening renal function and progression to End-Stage Renal Disease (ESRD) were observed during and after pregnancy, particularly in unplanned pregnancies.

Conclusions:

• CKD is often asymptomatic until advanced stages, making pregnancy a critical period for its detection.
• Appropriate management and specialist care during pregnancy can lead to better maternal and fetal health outcomes for individuals with CKD.