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Viewpoint: Recent Advances in Intracoronary Imaging for Vasa Vasorum Visualisation
Kensuke Nishimiya1, Yasuharu Matsumoto1, Hiroaki Shimokawa1
1Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine Sendai, Japan.
European Cardiology
|November 13, 2018
Summary
The coronary vasa vasorum (VV), small nutrient blood vessels in the artery wall, are increasingly recognized for their role in coronary atherosclerosis. Advanced imaging now allows in-human visualization, highlighting their clinical importance in heart disease.
Area of Science:
- Cardiovascular Biology
- Vascular Medicine
- Atherosclerosis Research
Background:
- The coronary adventitia contains the vasa vasorum (VV), a network of nutrient blood vessels crucial for arterial wall health.
- The VV is implicated in the pathogenesis of coronary atherosclerosis, a leading cause of heart disease.
- Traditionally difficult to study, the clinical significance of VV has gained attention.
Purpose of the Study:
- To highlight the role of coronary vasa vasorum in cardiovascular health and disease.
- To emphasize the impact of recent imaging advancements on VV research.
- To underscore the clinical relevance of VV in patients with coronary artery disease.
Main Methods:
- Review of current literature on coronary vasa vasorum.
- Discussion of advancements in intracoronary imaging techniques.
- Focus on in vivo visualization of coronary VV in humans.
Main Results:
- Coronary vasa vasorum (50-300 µm diameter) supply nutrients to the arterial wall.
- VV are increasingly recognized as a factor in coronary atherosclerosis development.
- Intracoronary imaging, like optical coherence tomography, enables in vivo visualization of human coronary VV.
Conclusions:
- Vasa vasorum are critical components of coronary artery physiology and pathology.
- Technological advances have opened new avenues for studying VV in vivo.
- Understanding coronary VV is clinically relevant for managing patients with coronary artery disease.
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