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Related Concept Videos

The Bronchial Tree01:23

The Bronchial Tree

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The human bronchi and bronchial tree play a crucial role in the respiratory system, facilitating the exchange of oxygen and carbon dioxide. Let's delve into the intricate structure and functions of these respiratory components.
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
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A schema is a mental construct consisting of a cluster or collection of related concepts (Bartlett, 1932). There are many different types of schemata, and they all have one thing in common: schemata are a method of organizing information that allows the brain to work more efficiently. When a schema is activated, the brain makes immediate assumptions about the person or object being observed.
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Related Experiment Video

Updated: Feb 2, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
14:39

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma

Published on: November 4, 2010

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Bronchial thermoplasty-an update.

Faria Nasim1, Vivek N Iyer1

  • 1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, USA.

Annals of Thoracic Medicine
|November 13, 2018
PubMed
Summary
This summary is machine-generated.

Bronchial thermoplasty, a non-drug treatment for severe asthma, uses radiofrequency energy to reduce airway smooth muscle. This review examines its FDA approval and compares it with new asthma medications.

Keywords:
AIR trialAQLQBronchial ThermoplastySevere Asthma

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Related Experiment Videos

Last Updated: Feb 2, 2026

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Area of Science:

  • Pulmonary Medicine
  • Medical Devices
  • Asthma Treatment

Background:

  • Severe asthma lacks effective non-pharmacological treatments.
  • Bronchial thermoplasty (BT) offers a device-based approach.
  • BT selectively ablates airway smooth muscle using radiofrequency energy.

Purpose of the Study:

  • To review the clinical trials supporting FDA approval of BT.
  • To evaluate BT within the FDA approval framework.
  • To discuss current guidelines and emerging pharmacological treatments for severe asthma.

Main Methods:

  • Appraisal of pivotal clinical trials for BT.
  • Analysis of the FDA approval process for medical devices.
  • Review of international guidelines on BT use.
  • Survey of recent advancements in severe asthma pharmacotherapy.

Main Results:

  • BT received FDA approval in 2010.
  • BT is the sole non-pharmacological, device-based therapy for severe asthma.
  • Evidence supports BT's efficacy in select severe asthma patients.

Conclusions:

  • BT represents a significant advancement in severe asthma management.
  • Understanding the regulatory pathway is crucial for device-based therapies.
  • Future directions include integrating BT with novel pharmacological agents.