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Related Concept Videos

Lung Capacity01:47

Lung Capacity

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The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
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Overview of Advanced Functional Groups02:22

Overview of Advanced Functional Groups

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Functional groups are groups of atoms with specific chemical properties that occur within organic molecules and are sometimes denoted as “R”. Functional groups can “functionalize” a compound by enabling it to adopt different physical and chemical properties.
Types of Advanced Functional Groups
The table below summarizes some of the major functional groups in organic chemistry.
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Extraction: Advanced Methods00:56

Extraction: Advanced Methods

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Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
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Sample Preparation for Analysis: Advanced Techniques01:08

Sample Preparation for Analysis: Advanced Techniques

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Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...
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Pleura of the Lungs01:13

Pleura of the Lungs

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The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
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Tissue Transplantation01:24

Tissue Transplantation

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Author Spotlight: Advancing Lung Transplant Immunology Through Intravital Imaging
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Author Spotlight: Advancing Lung Transplant Immunology Through Intravital Imaging

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Recent advances in lung transplantation.

Keith C Meyer1

  • 1UW Lung Transplant & Advanced Pulmonary Disease Program, Section of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

F1000Research
|November 13, 2018
PubMed
Summary

Lung transplantation offers improved survival for end-stage lung disease patients. Ongoing research addresses challenges like donor availability and post-transplant complications to enhance long-term success.

Keywords:
lung transplantation

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Area of Science:

  • Medicine
  • Immunology
  • Pulmonology

Background:

  • Lung transplantation is a vital treatment for end-stage lung disease, improving patient quality of life and survival.
  • Significant scientific and clinical advances have been made in lung transplantation over recent decades.

Purpose of the Study:

  • To review recent and evolving advances in lung transplantation.
  • To highlight key challenges and areas for future research in the field.

Main Methods:

  • Literature review of recent scientific and clinical research in lung transplantation.
  • Analysis of current challenges and proposed solutions in lung transplant medicine.

Main Results:

  • Advances in basic science and clinical research have improved lung transplant outcomes.
  • Key challenges remain, including donor pool expansion, tolerance induction, and managing complications like graft dysfunction and rejection.

Conclusions:

  • Continued research is essential to overcome existing barriers in lung transplantation.
  • Further advancements are needed to increase long-term post-transplant survival and allograft function.