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[Prostate cancer - screening and early detection].

Michael Borre1

  • 1mail: borre@clin.au.dk.

Ugeskrift for Laeger
|November 13, 2018
PubMed
Summary

Prostate cancer (PCa) screening aims to reduce mortality and maintain quality of life. However, current evidence advises against widespread screening due to controversy and diagnostic challenges.

Area of Science:

  • Urology
  • Oncology
  • Diagnostic Imaging

Background:

  • Population screening for prostate cancer (PCa) aims to decrease mortality and preserve quality of life.
  • Systematic population-based screening for PCa is highly controversial, with current findings recommending against it.
  • PCa is typically suspected through physical examination and prostate-specific antigen (PSA) levels.

Purpose of the Study:

  • To evaluate the role and impact of current prostate cancer screening methods.
  • To discuss the controversies surrounding population-based screening for PCa.
  • To highlight the diagnostic pathway for prostate cancer, including the role of multiparametric MRI.

Main Methods:

  • Review of current urological literature on prostate cancer screening.

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  • Analysis of diagnostic criteria for suspected prostate cancer.
  • Examination of the increasing use of multiparametric MRI (mpMRI) in the diagnostic pathway.

    • Main Results:

    • Prostate cancer screening remains a contentious issue in urology.
    • Strong recommendations exist against systematic population-based screening programs.
    • Multiparametric MRI is becoming a standard pre-biopsy tool for prostate cancer evaluation.

    Conclusions:

    • The benefits and risks of prostate cancer screening require careful consideration.
    • Diagnostic accuracy for PCa relies on histopathological verification following initial suspicion.
    • The integration of advanced imaging like mpMRI is crucial for improving diagnostic accuracy before biopsy.