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Related Experiment Video

Updated: Feb 2, 2026

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Preseptal Upper Eyelid Lipoma.

Michelle M Maeng1, Kyle J Godfrey, Michael Kazim

  • 1Edward S. Harkness Eye Institute, Columbia University Medical Center, New York, New York, U.S.A.

Ophthalmic Plastic and Reconstructive Surgery
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Summary

Eyelid lipomas, rare benign tumors, can occur in the preseptal plane, anterior to the orbital septum. This finding expands the differential diagnosis for painless, slow-growing eyelid masses in adults.

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Area of Science:

  • Ophthalmology
  • Dermatology
  • Surgical Pathology

Background:

  • Superficial subcutaneous lipomas are common, benign neoplasms of mature adipose cells, typically encapsulated.
  • While prevalent on the body, lipomas are infrequently documented in the eyelids.

Observation:

  • Previous reports located eyelid lipomas posterior to the orbital septum.
  • This case details a simple eyelid lipoma situated entirely within the preseptal plane, anterior to the orbital septum.

Findings:

  • Lipomas can indeed present anterior to the orbital septum.
  • The preseptal location of this eyelid lipoma is a novel observation.

Implications:

  • Clinicians should consider lipomas in the differential diagnosis of adult eyelid masses.
  • This expands the anatomical understanding of where eyelid lipomas can occur, aiding diagnosis and surgical planning.