Immunological therapy: A novel thriving area for triple-negative breast cancer treatment

Xiangyu Wang1, Yihang Qi2, Xiangyi Kong2

  • 1Department of Breast Surgical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China; Department of Laboratory Medicine, Mayo Clinic, Rochester, MN, 55902, USA.

Cancer Letters
|November 13, 2018
PubMed

Insights

Triple-negative breast cancer (TNBC) lacks targeted treatments. Immunotherapy offers a promising new avenue for treating this aggressive cancer, with ongoing research into various approaches.

Area of Science:

  • Oncology
  • Immunology
  • Cancer Research

Background:

  • Triple-negative breast cancer (TNBC) is an aggressive subtype lacking targeted therapies beyond chemotherapy.
  • Existing treatments for TNBC include surgery, chemotherapy, endocrine therapy, and molecular targeting therapy.
  • Immunotherapy represents a novel treatment modality for TNBC.

Purpose of the Study:

  • To review recent research advancements in immunotherapy for TNBC.
  • To provide a comprehensive overview of current and emerging immunotherapy strategies for TNBC.

Main Methods:

  • Review of recent scientific literature on TNBC immunotherapy.
  • Analysis of different immunotherapy approaches including active, passive, and oncolytic immunotherapy.
  • Exploration of TNBC molecular classification relevant to immunotherapy.

Main Results:

  • Immunotherapy is an emerging treatment for TNBC, distinct from traditional methods.
  • Research covers active, passive, and oncolytic immunotherapy strategies.
  • Molecular classification of TNBC is crucial for immunotherapy development.

Conclusions:

  • Immunotherapy holds significant promise for advancing TNBC treatment.
  • Further research into immunotherapy approaches is essential for clinical application.
  • The review highlights the evolving landscape of TNBC therapeutic options.

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