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Updated: Feb 2, 2026

Cross-Modal Multivariate Pattern Analysis
Published on: November 9, 2011
Subgroups of lifestyle patterns among hypertension patients: a latent-class analysis
Jalileh Ghanbari1, Asghar Mohammadpoorasl2,3, Leila Jahangiry4,5
1Health Education and Health Promotion Department, School of Public Health, Tabriz University of Medical Sciences, Tabriz, Iran.
Insights
This study identified three lifestyle risk groups for hypertension patients. Older age and widowed/divorced status increased risk, while higher education decreased it, informing targeted interventions.
Area of Science:
- Public Health
- Gerontology
- Cardiovascular Health
Background:
- Hypertension is a major preventable risk factor for disease and death.
- Identifying lifestyle and demographic patterns aids targeted health interventions.
- Understanding these patterns is crucial for effective hypertension management.
Purpose of the Study:
- To identify latent classes of lifestyle risk factors in hypertensive patients.
- To analyze demographic factors associated with these lifestyle patterns.
- To inform tailored prevention strategies for hypertension.
Main Methods:
- Latent class analysis (LCA) was used to cluster patients.
- Four modifiable lifestyle factors were assessed: diet, physical activity, smoking, and blood pressure control.
- 750 hypertensive patients from primary care centers in Takab, Iran, were recruited.
Main Results:
- Three distinct lifestyle risk classes were identified: low (14.4%), intermediate (54.6%), and high (31%).
- Increased age, widowed/divorced status were associated with higher risk class membership.
- Higher education levels were associated with decreased risk of intermediate and high-risk class membership.
Conclusions:
- Significant variations in lifestyle behaviors exist among hypertensive patient subgroups.
- The latent class approach effectively clusters co-occurring risk behaviors.
- Findings support targeted interventions focusing on multiple healthy behaviors for high-risk hypertensive patients.
Background:
Hypertension remains one of the most important preventable risk factors for diseases and death. Identifying clustered patterns of modifiable lifestyle risk factors for hypertension and demographics factors related to these clustered patterns allows for targeting health prevention interventions. Therefore, this study aims to identify latent classes of hypertensive patients' lifestyle risk factors based on the clustering of four modifiable lifestyle risk factors: eating, physical activity patterns, smoking habits, and blood pressure control.
Methods:
A total of 750 patients (Mage = 65.38 years, SDage = 9.2 years) with diagnosed hypertension in urban and rural primary health care centers in Takab (Iran) were recruited randomly from August 2016 to February 2017. Latent class analysis was performed by using proc. LCA in SAS 9.2.
Results:
Three classes of lifestyle patterns were identified. About 14.4% of hypertensive patients were categorized in a low-risk class (I), 54.6% in an intermediate-risk class (II), and 31% in a high-risk class (III) of lifestyle. A one-year increase in age significantly increases the risk of membership in classes II and III. Similarly, being widowed or divorced increases the risk of membership in classes II and III. Also, having a higher education level decreases the risk of membership in classes II and III.
Conclusions:
This study contributes to the literature on lifestyle behaviors among older adults and provides evidence that there are considerable differences in lifestyle behaviors between subgroups of older adult patients. The three profiles of hypertensive patients' conditions suggest that because behaviors often occur simultaneously within an individual level, a latent-class approach helps cluster co-occurrence risk behaviors and focuses on interventions targeted to several healthy behaviors among high-risk patients.
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