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Related Concept Videos

Skin Cancer01:30

Skin Cancer

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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Sensory Functions of the Skin01:16

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The skin is the largest organ of the human body and plays a crucial role in our sensory perception. It contains a vast network of sensory receptors that contribute to the skin's protective function by perceiving physical, biological, and environmental cues and generating relevant responses.
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Skin Diseases and Disorders01:23

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Role of Skin in Vitamin D Synthesis01:23

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The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
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Accessory Structures of the Skin: Nails01:05

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Nails are one of the important accessory structures of the skin. They are hard, protective structures that cover the dorsal surface of the distal phalanges of fingers and toes. Nails are composed of specialized keratinized cells and serve various functions, including protection, sensation, and manual dexterity.
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Changes in Skin Color: Clinical Perspectives01:14

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The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
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Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging
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Nonmelanoma Skin Cancer.

Michael G Brandt1, Corey C Moore2

  • 1Division of Facial Plastic and Reconstructive Surgery, Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, University of Toronto, 190 Elizabeth Street, Room 3S-438, TGH RFE Building, Toronto, Ontario M5G 2C4, Canada.

Facial Plastic Surgery Clinics of North America
|November 14, 2018
PubMed
Summary
This summary is machine-generated.

This review covers common head and neck nonmelanoma skin cancers. Complete tumor removal with clear margins is crucial, prioritizing oncologic principles over extensive reconstruction.

Keywords:
Adnexal carcinomas of the skinBasal cellKeratinocyte carcinomaMerkel cellNonmelanomaSarcomas of the skinSkin cancerSquamous cell

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Cell Population Analyses During Skin Carcinogenesis
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Area of Science:

  • Dermatology
  • Surgical Oncology
  • Head and Neck Surgery

Background:

  • Nonmelanoma skin cancers (NMSCs) frequently affect the head and neck.
  • While rarely fatal, NMSCs can cause significant local morbidity.
  • Tumor extirpation and reconstruction present unique challenges in this region.

Purpose of the Study:

  • To review common NMSCs in the head and neck.
  • To emphasize the importance of complete tumor extirpation with negative margins.
  • To discuss the balance between oncologic principles and reconstructive outcomes.

Main Methods:

  • Literature review of common NMSCs in the head and neck.
  • Discussion of surgical management principles.
  • Emphasis on achieving pathologically confirmed negative margins.

Main Results:

  • Complete tumor extirpation with negative margins is the standard of care.
  • Local morbidity from tumors and surgery is a significant concern.
  • Metastases are rare but require appropriate management.

Conclusions:

  • Prioritizing oncologic principles in NMSC management is paramount.
  • Reconstructive surgery should follow successful oncologic treatment.
  • Careful surgical planning is essential for optimal patient outcomes.