Related Experiment Video
Updated: Feb 2, 2026

Surgical Models of Gastroesophageal Reflux with Mice
Published on: August 25, 2015
The Modified Gil-Vernet Antireflux Surgery: A Successful Technique for High-Grade Vesicoureteral Reflux Correction in
Mahmoudreza Moradi1, Abolhassan Seyedzadeh2, Saeed Gharakhloo3
1Professor in Pediatric Urology, Chairman of Urology Department in Imam Reza Hospital, Chairman of Regenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.
Insights
Modified Gil-Vernet antireflux surgery effectively corrects high-grade vesicoureteral reflux (VUR) in children. This safe and simple technique demonstrated a high success rate in a retrospective study.
Area of Science:
- Pediatric Urology
- Surgical Techniques
- Urologic Anomalies
Background:
- Vesicoureteral reflux (VUR) is a prevalent congenital condition in pediatric patients.
- Various surgical interventions exist for VUR management, including the modified Gil-Vernet antireflux surgery.
Purpose of the Study:
- To assess the efficacy and safety of the modified Gil-Vernet antireflux surgery.
- To evaluate the outcomes of this technique in correcting high-grade VUR.
Main Methods:
- A retrospective analysis of patients who underwent modified Gil-Vernet antireflux surgery between 2000 and 2016.
- Evaluation of efficacy, safety, and complications in 183 patients with 290 refluxing units (grade IV or V).
Main Results:
- Successful correction of high-grade VUR in 95.86% of refluxing units and 95.62% of patients.
- The study included 183 patients, with 76 (41.54%) having unilateral and 107 (58.46%) having bilateral VUR.
Conclusions:
- Modified Gil-Vernet antireflux surgery is a simple, safe, and successful option for high-grade VUR.
- The technique allows for simultaneous correction of bilateral VUR, making it a rational choice.
- Results align with other established VUR correction techniques.
Introduction:
Vesicoureteral reflux (VUR) is a common urologic anomaly in children. Many techniques have been offered to manage this condition, in which one of them is modified Gil-Vernet antireflux surgery. The study fullfiled to evaluate the efficacy and safety of modified Gil-Vernet antireflux surgery in correction of high-grade VUR.
Materials And Methods:
A retrospective study in which we evaluated efficacy, safety, and complications of modified Gil-Vernet antireflux surgery as a choice procedure for high-grade reflux in all patients who underwent it since 2000 to 2016 at 2 hospitals of Kermanshah University of medical sciences that all of them were done by one surgeon.
Results:
183 patients with 290 high-grade refluxing units (grade IV or V) were reviewed. 182 refluxing units were grade IV, and 108 units were grade V. There were 76 (41.54%) patients with unilateral and 107 (58.46%) patients with bilateral VUR. Reflux in high-grade group corrected completely in 278 (95.86%) refluxing units and 175 patients (95.62%).
Conclusions:
Our results are remarkable and compatible with other techniques' results. This simple and safe technique can correct bilateral VURs simultaneously; thus, it is rational to be considered for high-grade VUR correction. According to our results, we suggest the modified Gil-Vernet antireflux procedure for high-grade VUR correction as a simple, safe, and successful technique. This trial is registered with 67145/86/1233.
Related Concept Videos
Ecological Succession
Distance Corrections
Power Factor Correction
Graded Potential
Graded potentials fall into two categories: depolarizing and hyperpolarizing. Depolarizing graded potentials typically occur when sodium (Na+) or...
Types of Aggregate Grading
Well-graded aggregates include a complete range of necessary size fractions that fit together to create a dense matrix with minimal voids, represented by a smooth, continuous gradation curve. This type of grading ensures good...
Long-term Depression

