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Updated: Feb 2, 2026

Gold Nanoparticle Synthesis
Published on: July 10, 2021
Smart Gold Nanoparticle-Stabilized Ultrasound Microbubbles as Cancer Theranostics
Young Il Yoon1,2, Xin Pang3, Sungwook Jung1
1Laboratory of Molecular Imaging and Nanomedicine (LOMIN), National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health (NIH), Bethesda, Maryland, 20892, USA.
Abstract:
Smart gold nanoparticle-stabilized microbubbles (SAuMBs) composed of a gas-filled core and shell including smart gold nanoparticles (SAuNPs) which can be aggregated in tumors were applied as ultrasound-mediated cancer theranostics. The gas core in the microstructure enabled the detection of tumors using ultrasound and facilitated the delivery of SAuNPs by sonoporation. The SAuNPs spontaneously aggregated in tumors, which allowed photoacoustic (PA) monitoring and photothermal treatment (PTT) of tumors.
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