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Published on: June 28, 2016
Optical manipulation of animal behavior using a ruthenium-based phototrigger
Yeraldith Rojas Pérez1, Roberto Etchenique1
1Departamento de Química Inorgánica, Analítica y Química Física, INQUIMAE, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, CONICET, Intendente Güiraldes 2160, Ciudad Universitaria, Pabellón 2, Buenos Aires (C1428EGA), Argentina. rober@qi.fcen.uba.ar.
Abstract:
A visible-light activatable caged compound based on a ruthenium-polypyridine complex was used to elicit the feeding response of the freshwater cnidarian Hydra vulgaris. The phototrigger delivers l-arginine in a clean reaction under irradiation with blue or green light. The synthesis, characterization and application mode of this caged arginine are described. A combination of fiber-optics setup and a high absorbance medium allows the precise control of uncaging in the submillimetric range, needed to address the zone where activation takes place.
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