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A Human Ex Vivo Atherosclerotic Plaque Model to Study Lesion Biology
Published on: May 6, 2014
BYPASS SURGERY IN PATIENTS WITH COMBINED ATHEROSCLEROTIC LESIONS OF COMMON AND INTERNAL CAROTID ARTERY
Insights
For chronic cerebrovascular disease patients with combined carotid artery lesions, surgical bypass is a viable option when endovascular treatments fail. This includes orthotopic or extraanatomic carotid artery bypass procedures.
Area of Science:
- Vascular Surgery
- Neurology
- Cardiology
Background:
- Chronic cerebrovascular disease affects numerous patients, often involving complex atherosclerotic lesions in the carotid arteries.
- Accurate diagnosis and treatment planning are crucial for managing patients with cerebrovascular disease.
Observation:
- A retrospective analysis of carotid angiographies was conducted on 146 patients with chronic cerebrovascular disease.
- Combined lesions of the common carotid artery and internal carotid artery with clinical manifestations were identified in 2 (1.4%) patients.
Findings:
- Surgical intervention, including crossed extraanatomic bypass and orthotopic common-internal autovenous bypass, was successfully performed in the identified patients.
- These bypass procedures effectively addressed combined atherosclerotic lesions in the common and internal carotid arteries.
Implications:
- Orthotopic or extraanatomic common-internal carotid artery bypasses are suggested as effective treatment alternatives when endovascular interventions are not feasible.
- This approach offers a solution for patients with combined atherosclerotic lesions in the common and internal carotid arteries, improving surgical outcomes.
Abstract:
An analysis of data of carotid angiographies was made in 146 patients with chronic cerebrovascular disease. Combined lesions of the common and internal carotid artery with clinical signs were revealed in 2 (1,4%) patients. A crossed extraanatomic bypass from the left common carotid artery to the right internal carotid artery was performed in one patient. The orthotopic common-internal autovenous bypass on the right side was carried out for another patient. According to obtained results, the authors suggested that the orthotopic or extraanatomic common-internal carotid artery bypasses could be applied in case of impossibility of endovascular intervention, when patients had the combined atherosclerotic lesions of common carotid and internal carotid artery.
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