Related Experiment Videos
The expression of S-100 protein and neuron-specific enolase in meningiomas
S A Jitawi1, A J Cochran, P A Cancilla
1Pathology Department of the King Hussein Medical Center, Amman, Jordan.
Disease Markers
|June 1, 1988
Abstract:
The distribution of S-100 protein and neuron-specific enolase (NSE) was examined in 19 meningiomas using the peroxidase-antiperoxidase (PAP) immunohistochemical technique. Positive cytoplasmic staining for NSE was observed in 16 tumors, and comparable staining for S-100 protein was observed in eight tumors. The finding of S-100 protein and NSE immunoreactivity in fibroblastic, meningiotheliomatous, and transitional meningiomas raises the possibility that these morphologically distinct neoplasms derive from a common pluripotential cell capable of differentiation along diverse paths.