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North American Contact Dermatitis Group Patch Test Results: 2015-2016.

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Summary

The North American Contact Dermatitis Group (NACDG) found methylisothiazolinone sensitivity continues. Comprehensive patch testing beyond screening series is vital for diagnosing allergic contact dermatitis (ACD).

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Area of Science:

  • Dermatology
  • Allergology
  • Epidemiology

Background:

  • Patch testing is crucial for diagnosing allergic contact dermatitis (ACD).
  • Understanding allergen prevalence is key to effective ACD management.

Purpose of the Study:

  • To report North American Contact Dermatitis Group (NACDG) patch testing results from 2015-2017.
  • To analyze trends in allergen sensitivity and identify common causes of ACD.

Main Methods:

  • Standardized patch testing with 70 allergens across 13 North American centers.
  • Data collection, verification, and statistical analysis including χ test for trend analysis.

Main Results:

  • Over 5,500 patients tested; 66.6% showed positive reactions, 50.2% diagnosed with ACD.
  • Nickel remained the most common allergen (17.5%), followed by methylisothiazolinone (13.4%).
  • Hydroxyethyl methacrylate showed a statistically significant increase in positive reactions.

Conclusions:

  • The high prevalence of methylisothiazolinone sensitivity persists in North America.
  • Patch testing with a broader range of allergens is essential for accurate ACD diagnosis, including occupational cases.