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Association Between Asthma and Depression: A National Cohort Study
Hyo Geun Choi1, Joo-Hee Kim2, Ji-Young Park2
1Departments of Otorhinolaryngology-Head & Neck Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
The Journal of Allergy and Clinical Immunology. in Practice
|November 14, 2018
Summary
Asthma and depression are linked. This study found that people with asthma are more likely to develop depression, and those with depression have a higher risk of developing asthma, indicating a two-way relationship.
Area of Science:
- Pulmonary Medicine
- Psychiatry
- Epidemiology
Background:
- Asthma and depression frequently co-occur in patients.
- The temporal sequence and bidirectional nature of this association remain unclear.
Purpose of the Study:
- To investigate the bidirectional relationship between asthma and depression in adults.
- Utilize a large-scale Korean national cohort for robust statistical analysis.
Main Methods:
- A national cohort from the Korean Health Insurance Review and Assessment Service was used.
- Matched cohorts of asthma patients and controls, and depression patients and controls were analyzed.
- Stratified Cox proportional hazards models assessed the hazard ratios for developing each condition.
Main Results:
- Patients with asthma had a significantly higher hazard ratio for developing depressive disorders (HR, 1.35; 95% CI, 1.31-1.40).
- Patients with depression exhibited a significantly higher hazard ratio for developing asthma (HR, 1.25; 95% CI, 1.21-1.29).
Conclusions:
- A significant bidirectional association exists between asthma and depression.
- Findings suggest that asthma may increase depression risk, and depression may increase asthma risk.
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